故事以两个主人公的约定而展开，讲述了虽然很贫穷却过得很幸福的少年“下町心”在唯一的亲人母亲过世后，落入了不幸的深渊。一位名叫“高城一希”的少年，也同样失去了姐姐。
When a mysterious figure began to target the evil of the national alchemist against God, the alchemist Edward Elric and his brother Alphonse were in the most vulnerable moment, at the same time, human beings began to unveil their own veil again.
